ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:07 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 292
Drug details and screening numbers
Drug Name: Masitinib
Drug ID: 292
Synonyms: AB1010
Brand name:
Target: KIT
Number of cell lines screened: 923
Screening concentration range(s): 0.078125 to 20 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a48 |
BCR-ABL_mut |
292 |
1 |
1 |
Masitinib |
KIT |
5 |
915 |
3 |
3.62 |
-0.696 |
-4.32 |
3.4 ** |
3.4 ** |
2.6 ** |
1.93e-07 |
8.32e-51 |
2.25e-01 |
0.066 |
a461 |
loss_cnaPANCAN99_(SOX17) |
292 |
1 |
1 |
Masitinib |
KIT |
48 |
872 |
3 |
3.56 |
4.32 |
0.759 |
0.58 . |
0.58 . |
0.61 . |
6.01e-04 |
6.73e-50 |
2.29e-01 |
21 |
a503 |
loss_cnaPANCAN326_(SOX9) |
292 |
1 |
1 |
Masitinib |
KIT |
10 |
910 |
3 |
3.58 |
5.04 |
1.46 |
1.1 * |
1.1 * |
1.2 * |
7.34e-04 |
7.08e-50 |
2.29e-01 |
24 |
All-tests volcano plot
