ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 306


Drug details and screening numbers

Drug Name: TG101348
Drug ID: 306
Synonyms:
Brand name:
Target: JAK2

Number of cell lines screened: 924
Screening concentration range(s): 0.04 to 10.24 uM


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a134

loss_cnaPANCAN326_(SOX9)

306

1

1

TG101348

JAK2

10

911

2.33

2.29

4.18

1.89

1.2 *

1.2 *

1.2 *

2.89e-05

1.14e-66

5.13e-01

3.5

a311

KDR_mut

306

1

1

TG101348

JAK2

9

912

2.33

2.29

4.11

1.82

1.2 *

1.2 *

2.2 **

2.72e-04

2.32e-66

5.14e-01

14

All-tests volcano plot