ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:45 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: KDR_mut
Feature details and cell panel numbers
Binary feature equal to 1 for samples harboring mutations in KDR
Number of cell lines positive for this feature: 9
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a124 |
KDR_mut |
152 |
1 |
1 |
CP466722 |
ATM |
9 |
914 |
2.77 |
2.6 |
4.36 |
1.76 |
1.3 * |
1.3 * |
1.6 * |
2.17e-05 |
3.25e-45 |
3.28e-01 |
2.9 |
a178 |
KDR_mut |
178 |
1 |
1 |
BAY 61-3606 |
SYK |
9 |
860 |
2.08 |
2.16 |
4.24 |
2.08 |
1.4 * |
1.4 * |
1.5 * |
6.05e-05 |
1.14e-16 |
3.54e-03 |
5.6 |
a311 |
KDR_mut |
306 |
1 |
1 |
TG101348 |
JAK2 |
9 |
912 |
2.33 |
2.29 |
4.11 |
1.82 |
1.2 * |
1.2 * |
2.2 ** |
2.72e-04 |
2.32e-66 |
5.14e-01 |
14 |
a455 |
KDR_mut |
194 |
1 |
1 |
AUY922 |
HSP90 |
9 |
854 |
-1.36 |
-2.92 |
-1.09 |
1.83 |
1.2 * |
1.2 * |
0.8 . |
5.88e-04 |
5.57e-10 |
4.77e-02 |
21 |
All-tests volcano plot
