ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:13 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 194


Drug details and screening numbers

Drug Name: AUY922
Drug ID: 194
Synonyms: VER-52296,NVP-AUY922
Brand name:
Target: HSP90

Number of cell lines screened: 866
Screening concentration range(s): 0.001 to 0.256 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a455	KDR_mut	194	1	1	AUY922	HSP90	9	854	-1.36	-2.92	-1.09	1.83	1.2 *	1.2 *	0.8 .	5.88e-04	5.57e-10	4.77e-02	21
a511	gain_cnaPANCAN84_(FGFR1,WHSC1L1)	194	1	1	AUY922	HSP90	65	798	-1.36	-2.97	-2.1	0.867	0.55 .	0.57 .	0.44	7.56e-04	5.68e-10	4.78e-02	24

All-tests volcano plot