ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 178


Drug details and screening numbers

Drug Name: BAY 61-3606
Drug ID: 178
Synonyms:
Brand name:
Target: SYK

Number of cell lines screened: 872
Screening concentration range(s): 0.03125 to 8 uM


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a178

KDR_mut

178

1

1

BAY 61-3606

SYK

9

860

2.08

2.16

4.24

2.08

1.4 *

1.4 *

1.5 *

6.05e-05

1.14e-16

3.54e-03

5.6

a420

gain_cnaPANCAN84_(FGFR1,WHSC1L1)

178

1

1

BAY 61-3606

SYK

65

804

2.08

2.11

3.05

0.944

0.63 .

0.63 .

0.64 .

5.15e-04

1.46e-16

3.62e-03

20

All-tests volcano plot