ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 152
Drug details and screening numbers
Drug Name: CP466722
Drug ID: 152
Synonyms: [2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine]
Brand name:
Target: ATM
Number of cell lines screened: 926
Screening concentration range(s): 0.0625 to 16 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a124 |
KDR_mut |
152 |
1 |
1 |
CP466722 |
ATM |
9 |
914 |
2.77 |
2.6 |
4.36 |
1.76 |
1.3 * |
1.3 * |
1.6 * |
2.17e-05 |
3.25e-45 |
3.28e-01 |
2.9 |
a246 |
EWSR1-FLI1_mut |
152 |
1 |
1 |
CP466722 |
ATM |
17 |
906 |
2.77 |
2.64 |
1.39 |
-1.25 |
0.92 . |
0.91 . |
1.5 * |
1.51e-04 |
5.15e-45 |
3.29e-01 |
10 |
a261 |
gain_cnaPANCAN18 |
152 |
1 |
1 |
CP466722 |
ATM |
53 |
870 |
2.77 |
2.57 |
3.41 |
0.841 |
0.62 . |
0.62 . |
0.66 . |
1.73e-04 |
5.31e-45 |
3.29e-01 |
11 |
a399 |
loss_cnaPANCAN369 |
152 |
1 |
1 |
CP466722 |
ATM |
110 |
813 |
2.77 |
2.54 |
3.13 |
0.591 |
0.44 |
0.44 |
0.4 |
4.58e-04 |
6.67e-45 |
3.3e-01 |
19 |
All-tests volcano plot
