ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:59 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: loss_cnaPANCAN369
Feature details and cell panel numbers
Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN369 deleted (see genomic region decoding file for further infos on this region)
Number of cell lines positive for this feature: 120
Statistically significant associations identified = 5
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a193 |
loss_cnaPANCAN369 |
1242 |
1 |
1 |
(5Z)-7-Oxozeaenol |
MAP3K7 (TAK1) |
115 |
798 |
2.3 |
0.734 |
1.49 |
0.76 |
0.54 . |
0.54 . |
0.52 . |
7.53e-05 |
2.33e-45 |
6.11e-01 |
6.4 |
a225 |
loss_cnaPANCAN369 |
1161 |
1 |
1 |
ZG-10 |
IRAK1 |
58 |
436 |
2.3 |
1.42 |
2.03 |
0.605 |
0.5 . |
0.53 . |
0.4 |
1.19e-04 |
4.46e-11 |
3.04e-01 |
8.7 |
a399 |
loss_cnaPANCAN369 |
152 |
1 |
1 |
CP466722 |
ATM |
110 |
813 |
2.77 |
2.54 |
3.13 |
0.591 |
0.44 |
0.44 |
0.4 |
4.58e-04 |
6.67e-45 |
3.3e-01 |
19 |
a482 |
loss_cnaPANCAN369 |
1143 |
1 |
1 |
HG-5-88-01 |
EGFR, ADCK4 |
58 |
435 |
2.3 |
3.17 |
3.67 |
0.5 |
0.4 |
0.39 |
0.48 |
6.68e-04 |
3.73e-10 |
1.3e-01 |
23 |
a521 |
loss_cnaPANCAN369 |
1248 |
1 |
1 |
FK866 |
NAMPT |
115 |
783 |
0 |
-2.74 |
-1.41 |
1.33 |
0.44 |
0.44 |
0.44 |
7.78e-04 |
8.94e-40 |
9.91e-04 |
25 |
All-tests volcano plot
