ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 331


Drug details and screening numbers

Drug Name: QL-X-138
Drug ID: 331
Synonyms:
Brand name:
Target: MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3

Number of cell lines screened: 911
Screening concentration range(s): 0.04 to 10.24 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a417

EWSR1-FLI1_mut

331

1

1

QL-X-138

MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3

17

891

2.33

1.58

0.146

-1.44

0.86 .

0.86 .

0.84 .

5.09e-04

5.45e-40

6.73e-01

20

All-tests volcano plot