ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 341


Drug details and screening numbers

Drug Name: EX-527
Drug ID: 341
Synonyms:
Brand name:
Target: SIRT1

Number of cell lines screened: 919
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a313

EWSR1-FLI1_mut

341

1

1

EX-527

SIRT1

17

899

3

5.4

5.07

-0.324

0.49

0.49

0.76 .

2.72e-04

5.9e-34

2.82e-01

14

All-tests volcano plot