ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 55


Drug details and screening numbers

Drug Name: A-770041
Drug ID: 55
Synonyms: A770041,KIN001-111
Brand name: A770041
Target: SRC family

Number of cell lines screened: 402
Screening concentration range(s): 0.02 to 5.12 uM


Statistically significant associations identified = 1

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a360

BCR-ABL_mut

55

1

1

A-770041

SRC family

5

396

1.63

2.1

-0.873

-2.97

1.7 *

1.7 *

2.7 **

3.65e-04

2.34e-07

5.94e-01

17

All-tests volcano plot