ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:55 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: NFE2L2_mut


Feature details and cell panel numbers

Binary feature equal to 1 for samples harboring mutations in NFE2L2

Number of cell lines positive for this feature: 14


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a164

NFE2L2_mut

94

1

1

TGX221

PI3Kbeta

3

397

2.3

3.84

1.74

-2.1

1.8 *

1.9 *

0.56 .

5.24e-05

9.67e-14

6.65e-01

5.2

a491

NFE2L2_mut

345

1

1

KIN001-270

CDK9

14

905

3

4.86

5.77

0.911

1 .

0.99 .

1.6 *

6.94e-04

6.74e-57

5.39e-02

23

All-tests volcano plot