ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:00 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: loss_cnaPANCAN368
Feature details and cell panel numbers
Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN368 deleted (see genomic region decoding file for further infos on this region)
Number of cell lines positive for this feature: 134
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a197 |
loss_cnaPANCAN368 |
176 |
1 |
1 |
IPA-3 |
PAK1, PAK2, PAK3 |
108 |
763 |
3.47 |
3.96 |
4.73 |
0.769 |
0.48 |
0.48 |
0.5 . |
8.1e-05 |
3.61e-24 |
3.63e-01 |
6.8 |
a528 |
loss_cnaPANCAN368 |
252 |
1 |
1 |
WZ3105 |
CLK2, CNSK1E, FLT3, ULK1 |
122 |
799 |
0.247, 2.326 |
0.0209 |
0.8 |
0.779 |
0.47 |
0.47 |
0.47 |
7.99e-04 |
1.3e-57 |
9.63e-01 |
25 |
All-tests volcano plot
