ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:00 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: loss_cnaPANCAN72


Feature details and cell panel numbers

Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN72 deleted (see genomic region decoding file for further infos on this region)

Number of cell lines positive for this feature: 7


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a196

loss_cnaPANCAN72

1028

1

1

VX-702

p38

5

839

0.693

2.89

1.57

-1.33

1.6 *

1.6 *

0.81 .

8.04e-05

4.9e-37

9.09e-01

6.8

a505

loss_cnaPANCAN72

1013

1

1

Nilotinib

ABL

5

795

0.693

2.66

1.06

-1.6

1.2 *

1.2 *

1.6 *

7.37e-04

5.5e-37

2.11e-01

24

All-tests volcano plot