Search results for : ali - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: ali

Drugs (12)
Genetic Features (2)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
Alisertib	MLN8237	AURKA	Mitosis		GDSC1	891	MGH
Alisertib	MLN8237	AURKA	Mitosis	24771867	GDSC2	949	SANGER
Idelalisib	CAL-101, Zydelig	PI3Kdelta	PI3K/MTOR signaling	11625818	GDSC1	914	MGH
Lenalidomide	CDC-501, CC-5013, Revlimid	CRBN	Protein stability and degradation	216326	GDSC1	933	SANGER
Lenalidomide	CDC-501, CC-5013, Revlimid	CRBN	Protein stability and degradation	216326	GDSC2	949	SANGER
Omipalisib	GSK2126458, GSK-2126458, EX-8678, GSK458	PI3K (class 1), MTORC1, MTORC2	PI3K/MTOR signaling	25167777	GDSC1	914	MGH
Oxaliplatin	Eloxatin	DNA alkylating agent	DNA replication	5310940	GDSC2	967	SANGER
Oxaliplatin		DNA alkylating agent	DNA replication		GDSC2	717	SANGER
Pilaralisib	XL-147	PI3K	PI3K/MTOR signaling		GDSC1	919	MGH
Tretinoin	ATRA, Vesanoid, Renova, Atralin, Tretin-X, Avita	Retinoic acid	Other	444795	GDSC1	923	SANGER
Tretinoin	ATRA, Vesanoid, Renova, Atralin, Tretin-X, Avita	Retinoic acid	Other	444795	GDSC2	225	SANGER
Voxtalisib	XL-765, SAR245409	PI3K (class 1), DNAPK, MTOR	PI3K/MTOR signaling		GDSC1	919	MGH

Feature Name	Feature Type
cnaLIHC10	copy number alteration (loss)
cnaLIHC7	copy number alteration (loss)

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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