Search results for : fo - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: fo

Drugs (9)
Celllines ( 4)
Genetic Features (1)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
BDOCA000347a	4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methylbenzenesulfonamide	BRPF1, BRPF2, BRPF3	Chromatin histone acetylation		GDSC2	717	SANGER
Bromosporine	ethyl N-[6-(3-methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate	CECR2, BRD2, BRD4, BRD9	Chromatin other		GDSC2	716	SANGER
Foretinib	GSK1363089, XL-880, EXEL-2880, GSK089	MET, KDR, TIE2, VEGFR3/FLT4, RON, PDGFR, FGFR1, EGFR	RTK signaling	42642645	GDSC1	909	MGH
Foretinib	GSK1363089, XL-880, EXEL-2880, GSK089	MET, KDR, TIE2, VEGFR3/FLT4, RON, PDGFR, FGFR1, EGFR	RTK signaling	42642645	GDSC2	953	SANGER
GSK2801	1-(7-(2-methylsulfonyl-phenyl)-4-propoxy-1-aza-bicyclo[4.3.0]nona-2,4,6,8-tetraen-9-yl)-ethanone		Chromatin other		GDSC2	717	SANGER
Methotrexate	Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex	Antimetabolite	DNA replication	126941	GDSC1	933	SANGER
Methotrexate	Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex	Antimetabolite	DNA replication	126941	GDSC2	881	SANGER
Phenformin	DBI	Biguanide agent	Other	8249	GDSC1	901	MGH
Pyrimethamine	Daraprim, Chloridine	Dihydrofolate reductase (DHFR)	Other	4993	GDSC1	398	MGH

Name	Cell Model Passport Link	COSMIC ID	Tissue	Tissue sub-type
EFO-21	SIDM01052	911905	OV	Urogenital system
EFO-21	SIDM01052	911905	OV	Urogenital system
EFO-27	SIDM01051	906852	UNCLASSIFIED	Urogenital system
EFO-27	SIDM01051	906852	UNCLASSIFIED	Urogenital system

Feature Name	Feature Type
FOXP1_mut	coding variant

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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