Search Results for: th

Name Synonyms Targets Target Pathway PubCHEM Datatset Sample size Screening site
Camptothecin Camptothecine, (+)-Camptothecin TOP1 DNA replication 24360 GDSC2 808 SANGER
DMOG Dimethyloxalylglcine HIF-PH Metabolism 560326 GDSC1 883 MGH
Doxorubicin Doxil, Rubex, Adriamycin, Adriablastin, Doxorubicine Anthracycline DNA replication 31703 GDSC1 877 MGH
Doxorubicin Anthracycline DNA replication GDSC1 934 SANGER
Epirubicin Ellence, Farmorubicin, IMI-28 Anthracycline DNA replication 41867 GDSC2 752 SANGER
Epothilone B Patupilone, EpoB, EPO906, GNF-PF-193 Microtubule stabiliser Mitosis 448013 GDSC1 875 MGH
Leflunomide Sulol, SU-101, HWA-486, Arava Pyrimidine synthesis inhibitor DNA replication 3899 GDSC2 728 SANGER
Methotrexate Abitrexate, Amethopterin, Rheumatrex, Trexall, Folex Antimetabolite DNA replication 126941 GDSC1 947 SANGER
Midostaurin PKC412, benzoylstaurosporine, CGP-41251 PKC, PPK, FLT1, c-FGR, others Other several GDSC1 888 MGH
Parthenolide HDAC1 Chromatin histone acetylation 7251185 GDSC1 401 MGH
Pyrimethamine Daraprim, Chloridine Dihydrofolate reductase (DHFR) Other 4993 GDSC1 399 MGH
SN-38 7-Ethyl-10-Hydroxy-Camptothecin, SN 38 TOP1 DNA replication 104842 GDSC1 952 SANGER
THZ-2-102-1 CDK7 Cell cycle none GDSC1 896 MGH
THZ-2-49 CDK9 Cell cycle none GDSC1 905 MGH
Thapsigargin Octanoic acid SERCA Other 446378 GDSC1 858 MGH
Tozasertib MK 0457,MK-0457,MK-045, VX-680 VX 680 VX-68 AURKA, AURKB, AURKC, others Mitosis 5494449 GDSC1 394 MGH
Tozasertib MK 0457,MK-0457,MK-045, VX-680 VX 680 VX-68 AURKA, AURKB, AURKC, others Mitosis 5494449 GDSC2 49 SANGER
UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 46224516 GDSC1 913 MGH
UNC0638 UNC-0638, UNC 0683 G9a and GLP methyltransferases Chromatin histone methylation 46224516 GDSC1 927 SANGER
WZ3105 SRC, ROCK2, NTRK2, FLT3, IRAK1, others Other none GDSC1 920 MGH
XMD14-99 ALK, CDK7, LTK, others Other, kinases none GDSC1 920 MGH
Zibotentan ZD4054, ZD-4054 Endothelin-1 receptor (EDNRA) Other 9910224 GDSC1 918 MGH
Name Cell Model Passport Link COSMIC ID Tissue Tissue sub-type
CGTH-W-1 SIDM01248 910568 THCA Thyroid
CGTH-W-1 SIDM01248 910568 THCA Thyroid
THP-1 SIDM01172 909771 LAML Blood
Feature Name Feature Type
THRAP3_mut coding variant

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