Search results for : zol - Cancerrxgene - Genomics of Drug Sensitivity in Cancer

Search Results for: zol

Drugs (11)

Name	Synonyms	Targets	Target Pathway	PubCHEM	Datatset	Sample size	Screening site
AICA Ribonucleotide	AICAR, N1-(b-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide	AMPK agonist	Metabolism	65110	GDSC1	925	SANGER
BDILV000379a	4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-4,5-dihydro-1H-imidazol-5-yl)benzonitrile	BAZ2A, BAZ2B	Chromatin histone acetylation		GDSC2	717	SANGER
BDOCA000347a	4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methylbenzenesulfonamide	BRPF1, BRPF2, BRPF3	Chromatin histone acetylation		GDSC2	717	SANGER
Bromosporine	ethyl N-[6-(3-methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate	CECR2, BRD2, BRD4, BRD9	Chromatin other		GDSC2	716	SANGER
Gallibiscoquinazole			Unclassified		GDSC2	717	SANGER
SGC-CBP30	8-(3-chloro-4-methoxy-phenethyl)-4-(3,5-dimethyl-isoxazol-4-yl)-9-(2-(morpholin-4-yl)-propyl)-7,9-diaza-bicyclo[4.3.0]nona-1(6),2,4,7-tetraene	EP300, CBP	Chromatin histone acetylation		GDSC2	716	SANGER
Temozolomide	Temodar, Temodal, M-39831, SCH 52365	DNA alkylating agent	DNA replication	5394	GDSC1	897	SANGER
Temozolomide	Temodar, Temodal, M-39831, SCH 52365	DNA alkylating agent	DNA replication	5394	GDSC2	965	SANGER
Vorinostat	Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683	HDAC inhibitor Class I, IIa, IIb, IV	Chromatin histone acetylation	5311	GDSC1	933	SANGER
Vorinostat	Zolinza, SAHA, suberanilohydroxamic acid, suberoylanilide hydroxamic acid, MK-0683	HDAC inhibitor Class I, IIa, IIb, IV	Chromatin histone acetylation	5311	GDSC2	959	SANGER
Zoledronate	Zoledronic acid, Zometa, Reclast		Other		GDSC2	717	SANGER

The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center (USA). This work is funded by Wellcome.

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