ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:06 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 1259
Drug details and screening numbers
Drug Name: BMN-673
Drug ID: 1259
Synonyms:
Brand name:
Target: PARP1
Number of cell lines screened: 915
Screening concentration range(s): 0.0390625 to 10 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a26 |
EWSR1-FLI1_mut |
1259 |
1 |
1 |
BMN-673 |
PARP1 |
18 |
894 |
2.3 |
2.18 |
-1.48 |
-3.66 |
2 ** |
2 ** |
1.5 * |
1.54e-09 |
4.9e-19 |
1.93e-03 |
0.00098 |
a189 |
loss_cnaPANCAN360 |
1259 |
1 |
1 |
BMN-673 |
PARP1 |
27 |
885 |
2.3 |
2.07 |
3.33 |
1.25 |
0.67 . |
0.66 . |
1.3 * |
7.04e-05 |
1.86e-18 |
2.17e-03 |
6.1 |
a398 |
EZH2_mut |
1259 |
1 |
1 |
BMN-673 |
PARP1 |
19 |
893 |
2.3 |
2.08 |
3.48 |
1.4 |
0.75 . |
0.74 . |
1.1 * |
4.56e-04 |
2.32e-18 |
2.22e-03 |
19 |
a523 |
loss_cnaPANCAN361 |
1259 |
1 |
1 |
BMN-673 |
PARP1 |
45 |
867 |
2.3 |
2.08 |
2.77 |
0.697 |
0.37 |
0.37 |
0.4 |
7.84e-04 |
2.47e-18 |
2.23e-03 |
25 |
All-tests volcano plot
