ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 1529


Drug details and screening numbers

Drug Name: MLN4924
Drug ID: 1529
Synonyms:
Brand name:
Target: NEDD8-activating enzyme

Number of cell lines screened: 703
Screening concentration range(s): 0.00390625 to 1 uM


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a159	gain_cnaPANCAN364_(STK4)	1529	1	1	MLN4924	NEDD8-activating enzyme	53	649	0	0.152	0.964	0.812	0.54 .	0.54 .	0.52 .	4.95e-05	1e-07	4.79e-02	5.1
a195	gain_cnaPANCAN363_(ASXL1)	1529	1	1	MLN4924	NEDD8-activating enzyme	76	626	0	0.13	0.896	0.766	0.51 .	0.51 .	0.48	7.82e-05	1.04e-07	4.8e-02	6.6

All-tests volcano plot