ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:34 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: gain_cnaPANCAN364_(STK4)


Feature details and cell panel numbers

Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN364_(STK4) amplified (see genomic region decoding file for further infos on this region)

Number of cell lines positive for this feature: 77


Statistically significant associations identified = 6

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a75	gain_cnaPANCAN364_(STK4)	1239	1	1	YK 4-279	RNA helicase A	58	734	2.3	1.5	2.24	0.745	0.59 .	0.6 .	0.51 .	3.2e-06	9.63e-09	4.34e-02	0.7
a99	gain_cnaPANCAN364_(STK4)	192	1	1	LFM-A13	BTK	68	803	2.77	4.58	5.04	0.451	0.62 .	0.62 .	0.67 .	1.18e-05	5.25e-12	1.98e-01	2
a110	gain_cnaPANCAN364_(STK4)	1378	1	1	Bleomycin (50 uM)	DNA damage	71	861	3.91	2.25	3.18	0.927	0.45	0.45	0.47	1.71e-05	3.99e-31	3.23e-04	2.6
a150	gain_cnaPANCAN364_(STK4)	208	1	1	SB-715992	KIF11	71	851	-2.06	-1.86	-0.726	1.13	0.64 .	0.64 .	0.77 .	3.83e-05	1.39e-33	1.88e-02	4.2
a159	gain_cnaPANCAN364_(STK4)	1529	1	1	MLN4924	NEDD8-activating enzyme	53	649	0	0.152	0.964	0.812	0.54 .	0.54 .	0.52 .	4.95e-05	1e-07	4.79e-02	5.1
a380	gain_cnaPANCAN364_(STK4)	257	1	1	NPK76-II-72-1	PLK3	70	849	2.33	2.77	3.88	1.1	0.65 .	0.64 .	0.85 .	3.95e-04	3.1e-75	3.81e-02	17

All-tests volcano plot