| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a81 |
SMARCA4_mut |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
50 |
882 |
3.91 |
2.39 |
1.23 |
-1.15 |
0.56 . |
0.56 . |
0.57 . |
4.45e-06 |
3.14e-31 |
3.16e-04 |
0.91 |
a110 |
gain_cnaPANCAN364_(STK4) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
71 |
861 |
3.91 |
2.25 |
3.18 |
0.927 |
0.45 |
0.45 |
0.47 |
1.71e-05 |
3.99e-31 |
3.23e-04 |
2.6 |
a112 |
TP53_mut |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
616 |
316 |
3.91 |
1.88 |
2.55 |
0.671 |
0.33 |
0.34 |
0.32 |
1.74e-05 |
4e-31 |
3.23e-04 |
2.6 |
a140 |
loss_cnaPANCAN145_(FANCG,PAX5) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
71 |
861 |
3.91 |
2.28 |
2.89 |
0.611 |
0.29 |
0.29 |
0.34 |
3.27e-05 |
4.48e-31 |
3.26e-04 |
3.9 |
a244 |
loss_cnaPANCAN308 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
91 |
841 |
3.91 |
2.23 |
3.22 |
0.991 |
0.48 |
0.47 |
0.56 . |
1.46e-04 |
5.83e-31 |
3.33e-04 |
9.9 |
a247 |
loss_cnaPANCAN232 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
46 |
886 |
3.91 |
2.27 |
3.35 |
1.07 |
0.52 . |
0.51 . |
0.66 . |
1.52e-04 |
5.87e-31 |
3.33e-04 |
10 |
a267 |
gain_cnaPANCAN363_(ASXL1) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
101 |
831 |
3.91 |
2.26 |
2.87 |
0.609 |
0.29 |
0.29 |
0.31 |
1.79e-04 |
6.04e-31 |
3.34e-04 |
11 |
a315 |
loss_cnaPANCAN305 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
76 |
856 |
3.91 |
2.24 |
3.29 |
1.05 |
0.51 . |
0.5 . |
0.61 . |
2.8e-04 |
6.53e-31 |
3.36e-04 |
15 |
a320 |
gain_cnaPANCAN366 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
82 |
850 |
3.91 |
2.27 |
2.93 |
0.665 |
0.32 |
0.32 |
0.33 |
2.84e-04 |
6.55e-31 |
3.36e-04 |
15 |
a324 |
loss_cnaPANCAN304 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
76 |
856 |
3.91 |
2.24 |
3.33 |
1.09 |
0.53 . |
0.53 . |
0.63 . |
2.94e-04 |
6.59e-31 |
3.36e-04 |
15 |
a326 |
loss_cnaPANCAN309 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
87 |
845 |
3.91 |
2.23 |
3.21 |
0.973 |
0.47 |
0.47 |
0.56 . |
2.96e-04 |
6.59e-31 |
3.36e-04 |
15 |
a330 |
loss_cnaPANCAN231 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
52 |
880 |
3.91 |
2.27 |
3.27 |
1 |
0.48 |
0.48 |
0.59 . |
2.99e-04 |
6.61e-31 |
3.36e-04 |
15 |
a340 |
gain_cnaPANCAN411_(BLM,CRTC3,FANCI,IDH2,NR2F2,PCSK6) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
27 |
905 |
3.91 |
2.29 |
3.56 |
1.27 |
0.62 . |
0.62 . |
0.62 . |
3.17e-04 |
6.68e-31 |
3.36e-04 |
15 |
a352 |
loss_cnaPANCAN307_(CHD3,GPS2,TP53) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
109 |
823 |
3.91 |
2.22 |
3.12 |
0.896 |
0.44 |
0.43 |
0.52 . |
3.52e-04 |
6.8e-31 |
3.37e-04 |
17 |
a379 |
loss_cnaPANCAN68 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
29 |
903 |
3.91 |
2.29 |
3.49 |
1.2 |
0.58 . |
0.58 . |
0.68 . |
3.94e-04 |
6.93e-31 |
3.37e-04 |
17 |
a433 |
loss_cnaPANCAN62_(HRAS,IRF7) |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
51 |
881 |
3.91 |
2.28 |
3.03 |
0.743 |
0.36 |
0.36 |
0.41 |
5.31e-04 |
7.3e-31 |
3.39e-04 |
20 |
a456 |
loss_cnaPANCAN224 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
13 |
919 |
3.91 |
2.3 |
4.04 |
1.74 |
0.84 . |
0.84 . |
0.96 . |
5.9e-04 |
7.44e-31 |
3.39e-04 |
21 |
a460 |
loss_cnaPANCAN63 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
40 |
892 |
3.91 |
2.29 |
3.05 |
0.762 |
0.37 |
0.37 |
0.41 |
5.97e-04 |
7.45e-31 |
3.39e-04 |
21 |
