ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:56 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: loss_cnaPANCAN309
Feature details and cell panel numbers
Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN309 deleted (see genomic region decoding file for further infos on this region)
Number of cell lines positive for this feature: 94
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a168 |
loss_cnaPANCAN309 |
1047 |
1 |
1 |
Nutlin-3a |
MDM2 |
77 |
769 |
2.08, 1.39 |
3.5 |
3.81 |
0.312 |
0.23 |
0.23 |
0.28 |
5.35e-05 |
6.91e-32 |
6.33e-02 |
5.3 |
a326 |
loss_cnaPANCAN309 |
1378 |
1 |
1 |
Bleomycin (50 uM) |
DNA damage |
87 |
845 |
3.91 |
2.23 |
3.21 |
0.973 |
0.47 |
0.47 |
0.56 . |
2.96e-04 |
6.59e-31 |
3.36e-04 |
15 |
All-tests volcano plot
