ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 185


Drug details and screening numbers

Drug Name: OSI-906
Drug ID: 185
Synonyms: OSI-906
Brand name:
Target: IGF1R

Number of cell lines screened: 871
Screening concentration range(s): 0.01 to 2.56 uM


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a130

NOTCH1_mut

185

1

1

OSI-906

IGF1R

16

852

0.94

2.11

0.687

-1.42

0.98 .

0.99 .

0.82 .

2.54e-05

1.27e-14

2.55e-01

3.2

a345

EWSR1-FLI1_mut

185

1

1

OSI-906

IGF1R

17

851

0.94

2.12

-0.118

-2.24

1.6 *

1.6 *

1.3 *

3.38e-04

1.67e-14

2.56e-01

16

All-tests volcano plot