ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:46 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: NOTCH1_mut


Feature details and cell panel numbers

Binary feature equal to 1 for samples harboring mutations in NOTCH1

Number of cell lines positive for this feature: 19


Statistically significant associations identified = 3

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a130	NOTCH1_mut	185	1	1	OSI-906	IGF1R	16	852	0.94	2.11	0.687	-1.42	0.98 .	0.99 .	0.82 .	2.54e-05	1.27e-14	2.55e-01	3.2
a137	NOTCH1_mut	184	1	1	BMS-754807	IGF1R	16	852	0.94	0.626	-0.965	-1.59	0.95 .	0.95 .	1 .	3.12e-05	1.41e-15	1.55e-01	3.8
a241	NOTCH1_mut	38	1	1	AZD-0530	SRC, ABL1	10	398	0.693	2.21	0.491	-1.71	1.5 *	1.5 *	0.94 .	1.39e-04	1.57e-05	6.4e-01	9.6

All-tests volcano plot