ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 200
Drug details and screening numbers
Drug Name: LAQ824
Drug ID: 200
Synonyms: Dacinostat, NVP-LAQ824
Brand name:
Target: HDAC
Number of cell lines screened: 876
Screening concentration range(s): 0.004 to 1.024 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a153 |
PIK3R1_mut |
200 |
1 |
1 |
LAQ824 |
HDAC |
23 |
850 |
0.0237 |
-2.8 |
-1.88 |
0.915 |
0.75 . |
0.77 . |
0.47 |
4.13e-05 |
5.55e-14 |
8.72e-01 |
4.5 |
a260 |
CHEK2_mut |
200 |
1 |
1 |
LAQ824 |
HDAC |
5 |
868 |
0.0237 |
-2.79 |
-0.706 |
2.08 |
1.7 * |
1.7 * |
0.97 . |
1.66e-04 |
6.38e-14 |
8.72e-01 |
11 |
a424 |
loss_cnaPANCAN170 |
200 |
1 |
1 |
LAQ824 |
HDAC |
11 |
862 |
0.0237 |
-2.79 |
-1.42 |
1.38 |
1.1 * |
1.1 * |
0.7 . |
5.18e-04 |
7.15e-14 |
8.72e-01 |
20 |
a486 |
loss_cnaPANCAN234 |
200 |
1 |
1 |
LAQ824 |
HDAC |
41 |
832 |
0.0237 |
-2.81 |
-2.08 |
0.727 |
0.6 . |
0.61 . |
0.45 |
6.82e-04 |
7.35e-14 |
8.73e-01 |
23 |
All-tests volcano plot
