ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 225
Drug details and screening numbers
Drug Name: Genentech Cpd 10
Drug ID: 225
Synonyms:
Brand name:
Target: AURKA, AURKB
Number of cell lines screened: 926
Screening concentration range(s): 0.04 to 10.24 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a184 |
EWSR1-FLI1_mut |
225 |
1 |
1 |
Genentech Cpd 10 |
AURKA, AURKB |
17 |
906 |
2.33 |
2.54 |
0.603 |
-1.93 |
1.1 * |
1.1 * |
1.2 * |
6.47e-05 |
4.73e-42 |
3.08e-01 |
5.8 |
a304 |
MLL2_mut |
225 |
1 |
1 |
Genentech Cpd 10 |
AURKA, AURKB |
97 |
826 |
2.33 |
2.58 |
1.8 |
-0.782 |
0.45 |
0.44 |
0.5 . |
2.52e-04 |
6.41e-42 |
3.09e-01 |
14 |
a525 |
loss_cnaPANCAN92 |
225 |
1 |
1 |
Genentech Cpd 10 |
AURKA, AURKB |
279 |
644 |
2.33 |
2.32 |
2.91 |
0.586 |
0.34 |
0.33 |
0.35 |
7.9e-04 |
8.25e-42 |
3.09e-01 |
25 |
All-tests volcano plot
