ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:07 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 271
Drug details and screening numbers
Drug Name: VNLG/124
Drug ID: 271
Synonyms: 4-(Butanoyloxymethyl)phenyl-(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoate
Brand name:
Target: HDAC, RAR
Number of cell lines screened: 919
Screening concentration range(s): 0.02 to 5.12 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a47 |
TET2_mut |
271 |
1 |
1 |
VNLG/124 |
HDAC, RAR |
18 |
898 |
1.63 |
3.82 |
2.18 |
-1.64 |
1.7 * |
1.8 * |
0.68 . |
1.82e-07 |
1.53e-67 |
2.2e-01 |
0.064 |
a123 |
CDKN1B_mut |
271 |
1 |
1 |
VNLG/124 |
HDAC, RAR |
6 |
910 |
1.63 |
3.8 |
1.8 |
-2 |
2.1 ** |
2.1 ** |
0.92 . |
2.13e-05 |
7.19e-67 |
2.23e-01 |
2.9 |
a458 |
EWSR1-FLI1_mut |
271 |
1 |
1 |
VNLG/124 |
HDAC, RAR |
17 |
899 |
1.63 |
3.8 |
2.96 |
-0.839 |
0.87 . |
0.87 . |
0.85 . |
5.96e-04 |
2.07e-66 |
2.24e-01 |
21 |
All-tests volcano plot
