ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 274
Drug details and screening numbers
Drug Name: PXD101, Belinostat
Drug ID: 274
Synonyms:
Brand name:
Target: HDAC
Number of cell lines screened: 896
Screening concentration range(s): 0.078125 to 20 uM
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a148 |
EWSR1-FLI1_mut |
274 |
1 |
1 |
PXD101, Belinostat |
HDAC |
17 |
876 |
3 |
0.305 |
-0.976 |
-1.28 |
0.68 . |
0.67 . |
1.2 * |
3.64e-05 |
4.62e-23 |
6.71e-01 |
4.1 |
a487 |
CLSPN_mut |
274 |
1 |
1 |
PXD101, Belinostat |
HDAC |
11 |
882 |
3 |
0.258 |
2.08 |
1.82 |
0.97 . |
0.97 . |
0.72 . |
6.91e-04 |
7.07e-23 |
6.72e-01 |
23 |
All-tests volcano plot
