ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:10 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: CLSPN_mut


Feature details and cell panel numbers

Binary feature equal to 1 for samples harboring mutations in CLSPN

Number of cell lines positive for this feature: 12


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a268	CLSPN_mut	272	1	1	AR-42	HDAC	11	899	1.63	-0.293	1.6	1.89	1.1 *	1.1 *	0.79 .	1.79e-04	3.02e-33	6.34e-01	11
a487	CLSPN_mut	274	1	1	PXD101, Belinostat	HDAC	11	882	3	0.258	2.08	1.82	0.97 .	0.97 .	0.72 .	6.91e-04	7.07e-23	6.72e-01	23

All-tests volcano plot