ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08
iorio@ebi.ac.uk


Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 294


Drug details and screening numbers

Drug Name: MPS-1-IN-1
Drug ID: 294
Synonyms:
Brand name:
Target: MPS1

Number of cell lines screened: 920
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 3
association id
FEATURE
Drug id
Propr
Public
Drug Name
Drug Target
N FEATURE pos
N FEATURE neg
log max Conc tested
FEATURE neg logIC50 MEAN
FEATURE pos logIC50 MEAN
FEATURE deltaMEAN IC50
FEATURE IC50 effectSize
FEATURE neg Glass delta
FEATURE pos Glass delta
ANOVA FEATURE pval
Tissue ANOVA pval
MSI ANOVA pval
ANOVA FEATURE FDR %
a70
EWSR1-FLI1_mut
294
1
1
MPS-1-IN-1
MPS1
17
900
3
3.8
1.97
-1.84
1.4 *
1.3 *
1.9 *
2.87e-06
9.63e-43
7.06e-01
0.68
a329
MLL2_mut
294
1
1
MPS-1-IN-1
MPS1
96
821
3
3.84
3.17
-0.672
0.49
0.48
0.58 .
2.98e-04
2.78e-42
7.08e-01
15
a359
gain_cnaPANCAN367_(ARFGAP1,GNAS)
294
1
1
MPS-1-IN-1
MPS1
115
802
3
3.68
4.39
0.706
0.52 .
0.52 .
0.54 .
3.64e-04
2.91e-42
7.08e-01
17


All-tests volcano plot