ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 303


Drug details and screening numbers

Drug Name: PIK-93
Drug ID: 303
Synonyms:
Brand name:
Target: PI4K, PI3K

Number of cell lines screened: 922
Screening concentration range(s): 0.078125 to 20 uM


Statistically significant associations identified = 2

association id

FEATURE

Drug id

Propr

Public

Drug Name

Drug Target

N FEATURE pos

N FEATURE neg

log max Conc tested

FEATURE neg logIC50 MEAN

FEATURE pos logIC50 MEAN

FEATURE deltaMEAN IC50

FEATURE IC50 effectSize

FEATURE neg Glass delta

FEATURE pos Glass delta

ANOVA FEATURE pval

Tissue ANOVA pval

MSI ANOVA pval

ANOVA FEATURE FDR %

a122

EWSR1-FLI1_mut

303

1

1

PIK-93

PI4K, PI3K

17

902

3

2.7

0.895

-1.81

1.1 *

1.1 *

1.2 *

2.08e-05

9.86e-66

2.13e-01

2.8

a494

MLL2_mut

303

1

1

PIK-93

PI4K, PI3K

96

823

3

2.75

1.96

-0.791

0.47

0.47

0.46

7e-04

2.96e-65

2.15e-01

23

All-tests volcano plot