ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 304
Drug details and screening numbers
Drug Name: SB52334
Drug ID: 304
Synonyms:
Brand name:
Target: ALK5
Number of cell lines screened: 921
Screening concentration range(s): 0.078125 to 20 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a177 |
EWSR1-FLI1_mut |
304 |
1 |
1 |
SB52334 |
ALK5 |
17 |
901 |
3 |
4.25 |
2.5 |
-1.76 |
1.4 * |
1.4 * |
1.3 * |
6.04e-05 |
5.22e-23 |
5.26e-01 |
5.6 |
a317 |
MLL2_mut |
304 |
1 |
1 |
SB52334 |
ALK5 |
96 |
822 |
3 |
4.26 |
3.9 |
-0.354 |
0.28 |
0.28 |
0.29 |
2.82e-04 |
6.49e-23 |
5.26e-01 |
15 |
a407 |
EWSR1-X_mut |
304 |
1 |
1 |
SB52334 |
ALK5 |
5 |
913 |
3 |
4.23 |
1.77 |
-2.46 |
2 * |
2 * |
1.8 * |
4.88e-04 |
7.01e-23 |
5.27e-01 |
20 |
All-tests volcano plot
