ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:08 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 328


Drug details and screening numbers

Drug Name: SNX-2112
Drug ID: 328
Synonyms:
Brand name:
Target: HSP90

Number of cell lines screened: 914
Screening concentration range(s): 0.01 to 2.56 uM


Statistically significant associations identified = 3

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a115	EWSR1-FLI1_mut	328	1	1	SNX-2112	HSP90	17	894	0.94	-0.541	-2.39	-1.85	0.86 .	0.85 .	1.4 *	1.91e-05	2.54e-43	1.74e-01	2.7
a422	gain_cnaPANCAN108_(CHD9,CYLD)	328	1	1	SNX-2112	HSP90	26	885	0.94	-0.628	1.23	1.86	0.86 .	0.86 .	1.1 *	5.17e-04	5.45e-43	1.76e-01	20
a469	MLL2_mut	328	1	1	SNX-2112	HSP90	95	816	0.94	-0.461	-1.56	-1.1	0.51 .	0.51 .	0.56 .	6.13e-04	5.66e-43	1.76e-01	22

All-tests volcano plot