ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:33 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual Feature analysis: loss_cnaPANCAN312
Feature details and cell panel numbers
Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN312 deleted (see genomic region decoding file for further infos on this region)
Number of cell lines positive for this feature: 91
Statistically significant associations identified = 2
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a66 |
loss_cnaPANCAN312 |
1047 |
1 |
1 |
Nutlin-3a |
MDM2 |
75 |
771 |
2.08, 1.39 |
3.48 |
3.95 |
0.466 |
0.35 |
0.34 |
0.43 |
2.41e-06 |
3.73e-32 |
6.24e-02 |
0.6 |
a385 |
loss_cnaPANCAN312 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
80 |
838 |
1.61 |
3.39 |
3.74 |
0.349 |
0.35 |
0.35 |
0.43 |
4.13e-04 |
9.33e-15 |
1.23e-01 |
18 |
All-tests volcano plot
