| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a182 |
EWSR1-FLI1_mut |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
17 |
901 |
1.61 |
3.45 |
1.99 |
-1.46 |
1.5 * |
1.5 * |
1 * |
6.4e-05 |
7.74e-15 |
1.23e-01 |
5.8 |
a204 |
loss_cnaPANCAN229 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
33 |
885 |
1.61 |
3.39 |
4.16 |
0.77 |
0.79 . |
0.78 . |
1 * |
9.06e-05 |
8.02e-15 |
1.23e-01 |
7.3 |
a215 |
loss_cnaPANCAN227, loss_cnaPANCAN228 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
31 |
887 |
1.61 |
3.4 |
4.15 |
0.758 |
0.77 . |
0.77 . |
0.98 . |
1.03e-04 |
8.12e-15 |
1.23e-01 |
7.9 |
a314 |
loss_cnaPANCAN218 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
30 |
888 |
1.61 |
3.4 |
4.09 |
0.686 |
0.7 . |
0.69 . |
0.94 . |
2.73e-04 |
8.96e-15 |
1.23e-01 |
14 |
a323 |
loss_cnaPANCAN311 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
83 |
835 |
1.61 |
3.39 |
3.75 |
0.357 |
0.36 |
0.36 |
0.44 |
2.91e-04 |
9.01e-15 |
1.23e-01 |
15 |
a361 |
loss_cnaPANCAN307_(CHD3,GPS2,TP53) |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
104 |
814 |
1.61 |
3.39 |
3.68 |
0.286 |
0.29 |
0.28 |
0.36 |
3.65e-04 |
9.22e-15 |
1.23e-01 |
17 |
a385 |
loss_cnaPANCAN312 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
80 |
838 |
1.61 |
3.39 |
3.74 |
0.349 |
0.35 |
0.35 |
0.43 |
4.13e-04 |
9.33e-15 |
1.23e-01 |
18 |
a395 |
loss_cnaPANCAN305 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
70 |
848 |
1.61 |
3.39 |
3.77 |
0.377 |
0.38 |
0.38 |
0.45 |
4.44e-04 |
9.4e-15 |
1.24e-01 |
19 |
a480 |
loss_cnaPANCAN308 |
1175 |
1 |
1 |
AG-014699 |
PARP1, PARP2 |
87 |
831 |
1.61 |
3.39 |
3.71 |
0.314 |
0.32 |
0.31 |
0.39 |
6.66e-04 |
9.78e-15 |
1.24e-01 |
23 |
