ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:22 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: loss_cnaPANCAN93


Feature details and cell panel numbers

Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN93 deleted (see genomic region decoding file for further infos on this region)

Number of cell lines positive for this feature: 115


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a336	loss_cnaPANCAN93	1057	1	1	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	87	752	-1.386, 0.693	-2.51	-1.91	0.605	0.5 .	0.51 .	0.47	3.09e-04	9.64e-14	2.81e-02	15
a488	loss_cnaPANCAN93	1129	1	1	PF-4708671	RPS6KB1 (p70S6KA)	105	800	2.3	3.79	4.19	0.402	0.43	0.42	0.54 .	6.92e-04	6.98e-08	6.89e-02	23

All-tests volcano plot