ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:07 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 221
Drug details and screening numbers
Drug Name: TAK-715
Drug ID: 221
Synonyms: KIN001-201
Brand name:
Target: p38a
Number of cell lines screened: 927
Screening concentration range(s): 0.078125 to 20 uM and 0.04 to 10.24 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a58 |
EWSR1-FLI1_mut |
221 |
1 |
1 |
TAK-715 |
p38a |
17 |
907 |
3.00, 2.33 |
4.19 |
3.29 |
-0.897 |
0.76 . |
0.76 . |
0.85 . |
1.22e-06 |
1.54e-54 |
2.29e-01 |
0.35 |
a88 |
loss_cnaPANCAN234 |
221 |
1 |
1 |
TAK-715 |
p38a |
45 |
879 |
3.00, 2.33 |
4.13 |
4.96 |
0.833 |
0.71 . |
0.71 . |
0.75 . |
6.37e-06 |
2.43e-54 |
2.3e-01 |
1.2 |
a145 |
loss_cnaPANCAN233 |
221 |
1 |
1 |
TAK-715 |
p38a |
48 |
876 |
3.00, 2.33 |
4.13 |
4.92 |
0.791 |
0.67 . |
0.67 . |
0.72 . |
3.56e-05 |
3.89e-54 |
2.31e-01 |
4.1 |
All-tests volcano plot
