ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:11 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 222
Drug details and screening numbers
Drug Name: BX-912
Drug ID: 222
Synonyms: KIN001-175
Brand name:
Target: PDPK1 (PDK1)
Number of cell lines screened: 924
Screening concentration range(s): 0.04 to 10.24 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a291 |
EWSR1-FLI1_mut |
222 |
1 |
1 |
BX-912 |
PDPK1 (PDK1) |
16 |
905 |
2.33 |
2.78 |
0.793 |
-1.99 |
1.1 * |
1.1 * |
1.3 * |
2.17e-04 |
4e-62 |
3.73e-01 |
12 |
a518 |
XRN1_mut |
222 |
1 |
1 |
BX-912 |
PDPK1 (PDK1) |
15 |
906 |
2.33 |
2.77 |
1.39 |
-1.38 |
0.77 . |
0.77 . |
0.61 . |
7.75e-04 |
5.83e-62 |
3.74e-01 |
25 |
a526 |
MLL2_mut |
222 |
1 |
1 |
BX-912 |
PDPK1 (PDK1) |
97 |
824 |
2.33 |
2.83 |
2.06 |
-0.768 |
0.43 |
0.43 |
0.43 |
7.9e-04 |
5.87e-62 |
3.74e-01 |
25 |
All-tests volcano plot
