ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:06 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 260
Drug details and screening numbers
Drug Name: NG-25
Drug ID: 260
Synonyms:
Brand name:
Target: MAP3K7 (TAK1)
Number of cell lines screened: 922
Screening concentration range(s): 0.04 to 10.24 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a11 |
BCR-ABL_mut |
260 |
1 |
1 |
NG-25 |
MAP3K7 (TAK1) |
5 |
914 |
2.33 |
2.67 |
-4.22 |
-6.89 |
4.2 ** |
4.2 ** |
13 ** |
8.52e-12 |
5.68e-63 |
9.08e-01 |
1.3e-05 |
a98 |
NRAS_mut |
260 |
1 |
1 |
NG-25 |
MAP3K7 (TAK1) |
58 |
861 |
2.33 |
2.63 |
2.62 |
-0.016 |
0.0094 |
0.0092 |
0.012 |
9.73e-06 |
4.23e-61 |
9.1e-01 |
1.6 |
a206 |
MLL2_mut |
260 |
1 |
1 |
NG-25 |
MAP3K7 (TAK1) |
96 |
823 |
2.33 |
2.72 |
1.9 |
-0.814 |
0.48 |
0.48 |
0.47 |
9.17e-05 |
8.26e-61 |
9.1e-01 |
7.3 |
All-tests volcano plot
