ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:06 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 277
Drug details and screening numbers
Drug Name: ABT-869
Drug ID: 277
Synonyms: Linifanib
Brand name:
Target: VEGFR and PDGFR family
Number of cell lines screened: 924
Screening concentration range(s): 0.004 to 1.024 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a14 |
FLT3_mut |
277 |
1 |
1 |
ABT-869 |
VEGFR and PDGFR family |
11 |
910 |
0.0237 |
2.3 |
0.585 |
-1.72 |
1.8 * |
1.9 * |
0.5 . |
1.5e-10 |
1.19e-27 |
9.51e-01 |
0.00017 |
a27 |
U2AF1_mut |
277 |
1 |
1 |
ABT-869 |
VEGFR and PDGFR family |
5 |
916 |
0.0237 |
2.3 |
-0.318 |
-2.62 |
2.8 ** |
2.9 ** |
0.68 . |
4.21e-09 |
2.08e-27 |
9.51e-01 |
0.0026 |
a71 |
CDKN1B_mut |
277 |
1 |
1 |
ABT-869 |
VEGFR and PDGFR family |
6 |
915 |
0.0237 |
2.3 |
0.101 |
-2.2 |
2.3 ** |
2.4 ** |
0.74 . |
3e-06 |
6.14e-27 |
9.52e-01 |
0.68 |
All-tests volcano plot
