| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a27 |
U2AF1_mut |
277 |
1 |
1 |
ABT-869 |
VEGFR and PDGFR family |
5 |
916 |
0.0237 |
2.3 |
-0.318 |
-2.62 |
2.8 ** |
2.9 ** |
0.68 . |
4.21e-09 |
2.08e-27 |
9.51e-01 |
0.0026 |
a43 |
U2AF1_mut |
254 |
1 |
1 |
AC220 |
FLT3 |
5 |
915 |
0.0237 |
2.15 |
-0.515 |
-2.66 |
2.5 ** |
2.6 ** |
0.62 . |
8.26e-08 |
2.85e-48 |
9.4e-01 |
0.032 |
a72 |
U2AF1_mut |
30 |
1 |
1 |
Sorafenib |
PDGFRA, PDGFRB, KDR, KIT, FLT3 |
3 |
400 |
1.39 |
2.06 |
-1.53 |
-3.6 |
2.8 ** |
2.8 ** |
1 * |
3.04e-06 |
1.99e-04 |
1.15e-02 |
0.68 |
a171 |
U2AF1_mut |
5 |
1 |
1 |
Sunitinib |
PDGFRA, PDGFRB, KDR, KIT, FLT3 |
3 |
397 |
2.08 |
2.43 |
-1.65 |
-4.09 |
2.5 ** |
2.5 ** |
2.7 ** |
5.59e-05 |
1.01e-11 |
1.71e-01 |
5.4 |
a240 |
U2AF1_mut |
249 |
1 |
1 |
XL-184 |
VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL |
5 |
914 |
1.63 |
2.7 |
0.172 |
-2.53 |
1.9 * |
1.9 * |
0.68 . |
1.35e-04 |
1.24e-26 |
2.89e-01 |
9.3 |
