ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:10 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 287
Drug details and screening numbers
Drug Name: KIN001-244
Drug ID: 287
Synonyms:
Brand name:
Target: PDPK1 (PDK1)
Number of cell lines screened: 921
Screening concentration range(s): 0.078125 to 20 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a202 |
MLL2_mut |
287 |
1 |
1 |
KIN001-244 |
PDPK1 (PDK1) |
95 |
823 |
3 |
3.34 |
2.74 |
-0.601 |
0.48 |
0.49 |
0.44 |
8.84e-05 |
2.26e-42 |
6.13e-01 |
7.2 |
a300 |
EWSR1-FLI1_mut |
287 |
1 |
1 |
KIN001-244 |
PDPK1 (PDK1) |
17 |
901 |
3 |
3.3 |
2.38 |
-0.92 |
0.73 . |
0.73 . |
0.9 . |
2.4e-04 |
2.83e-42 |
6.13e-01 |
13 |
a373 |
loss_cnaPANCAN360 |
287 |
1 |
1 |
KIN001-244 |
PDPK1 (PDK1) |
25 |
893 |
3 |
3.26 |
4.02 |
0.76 |
0.6 . |
0.6 . |
0.62 . |
3.83e-04 |
3.15e-42 |
6.14e-01 |
17 |
a509 |
loss_cnaPANCAN359_(CUL3) |
287 |
1 |
1 |
KIN001-244 |
PDPK1 (PDK1) |
18 |
900 |
3 |
3.26 |
4.2 |
0.942 |
0.75 . |
0.75 . |
0.94 . |
7.52e-04 |
3.66e-42 |
6.14e-01 |
24 |
All-tests volcano plot
