ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:06 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 295
Drug details and screening numbers
Drug Name: NVP-BHG712
Drug ID: 295
Synonyms:
Brand name:
Target: EPHB4
Number of cell lines screened: 922
Screening concentration range(s): 0.04 to 10.24 uM
Statistically significant associations identified = 3
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a24 |
BCR-ABL_mut |
295 |
1 |
1 |
NVP-BHG712 |
EPHB4 |
5 |
914 |
2.33 |
3.03 |
-3.32 |
-6.35 |
4 ** |
4 ** |
13 ** |
7.49e-10 |
3.82e-67 |
4.71e-01 |
0.00052 |
a64 |
MLL2_mut |
295 |
1 |
1 |
NVP-BHG712 |
EPHB4 |
96 |
823 |
2.33 |
3.09 |
2.17 |
-0.914 |
0.56 . |
0.56 . |
0.52 . |
2.39e-06 |
5.25e-66 |
4.75e-01 |
0.6 |
a111 |
BRAF_mut |
295 |
1 |
1 |
NVP-BHG712 |
EPHB4 |
78 |
841 |
2.33 |
3.06 |
2.29 |
-0.77 |
0.47 |
0.46 |
0.53 . |
1.73e-05 |
9.85e-66 |
4.76e-01 |
2.6 |
All-tests volcano plot
