ANOVA PANCAN result package
Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:07 iorio@ebi.ac.uk
Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer
Individual drug analysis: 310
Drug details and screening numbers
Drug Name: YM201636
Drug ID: 310
Synonyms:
Brand name:
Target: FYV1
Number of cell lines screened: 922
Screening concentration range(s): 0.02 to 5.12 uM
Statistically significant associations identified = 4
| association id |
FEATURE |
Drug id |
Propr |
Public |
Drug Name |
Drug Target |
N FEATURE pos |
N FEATURE neg |
log max Conc tested |
FEATURE neg logIC50 MEAN |
FEATURE pos logIC50 MEAN |
FEATURE deltaMEAN IC50 |
FEATURE IC50 effectSize |
FEATURE neg Glass delta |
FEATURE pos Glass delta |
ANOVA FEATURE pval |
Tissue ANOVA pval |
MSI ANOVA pval |
ANOVA FEATURE FDR % |
a33 |
EWSR1-FLI1_mut |
310 |
1 |
1 |
YM201636 |
FYV1 |
17 |
902 |
1.63 |
2.31 |
0.552 |
-1.76 |
1.4 * |
1.4 * |
1.5 * |
1.71e-08 |
2.74e-37 |
1.55e-02 |
0.0086 |
a185 |
MLL2_mut |
310 |
1 |
1 |
YM201636 |
FYV1 |
96 |
823 |
1.63 |
2.35 |
1.66 |
-0.686 |
0.55 . |
0.54 . |
0.57 . |
6.53e-05 |
1.52e-36 |
1.64e-02 |
5.8 |
a243 |
loss_cnaPANCAN360 |
310 |
1 |
1 |
YM201636 |
FYV1 |
25 |
894 |
1.63 |
2.26 |
3.03 |
0.771 |
0.61 . |
0.61 . |
0.79 . |
1.45e-04 |
1.78e-36 |
1.65e-02 |
9.8 |
a512 |
loss_cnaPANCAN326_(SOX9) |
310 |
1 |
1 |
YM201636 |
FYV1 |
10 |
909 |
1.63 |
2.26 |
3.67 |
1.41 |
1.1 * |
1.1 * |
1.3 * |
7.59e-04 |
2.48e-36 |
1.67e-02 |
24 |
All-tests volcano plot
