ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:01:09 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual drug analysis: 110


Drug details and screening numbers

Drug Name: Roscovitine
Drug ID: 110
Synonyms: Seliciclib
Brand name:
Target: CDKs

Number of cell lines screened: 398
Screening concentration range(s): 0.0625 to 16 uM


Statistically significant associations identified = 5

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a174	loss_cnaPANCAN304	110	1	1	Roscovitine	CDKs	43	354	2.77	3.87	4.36	0.485	0.5 .	0.5 .	0.51 .	6.01e-05	1.8e-04	8.98e-01	5.6
a175	loss_cnaPANCAN305	110	1	1	Roscovitine	CDKs	43	354	2.77	3.87	4.36	0.485	0.5 .	0.5 .	0.51 .	6.01e-05	1.8e-04	8.98e-01	5.6
a176	loss_cnaPANCAN306	110	1	1	Roscovitine	CDKs	43	354	2.77	3.87	4.36	0.485	0.5 .	0.5 .	0.51 .	6.01e-05	1.8e-04	8.98e-01	5.6
a338	loss_cnaPANCAN310_(MAP2K4)	110	1	1	Roscovitine	CDKs	48	349	2.77	3.87	4.33	0.454	0.47	0.47	0.47	3.13e-04	2.07e-04	8.98e-01	15
a364	loss_cnaPANCAN308	110	1	1	Roscovitine	CDKs	47	350	2.77	3.87	4.32	0.442	0.46	0.46	0.42	3.67e-04	2.1e-04	8.98e-01	17

All-tests volcano plot